Download PDF by Stephen J. Lippard (auth.), Dimitris P. Kessissoglou (eds.): Bioinorganic Chemistry: An Inorganic Perspective of Life

By Stephen J. Lippard (auth.), Dimitris P. Kessissoglou (eds.)

ISBN-10: 940104113X

ISBN-13: 9789401041133

ISBN-10: 9401102554

ISBN-13: 9789401102551

Bioinorganic chemistry is basically considering the position of steel atoms in biology and is a truly energetic examine box. even if, although such vital buildings of metalloenzymes are identified, because the MoFeCo of nitrogenase, Cu or Mn superoxide dismutase and plastocyanin, the substitute routes to the modelling of such facilities is still a question of acute medical curiosity. different metalloenzymes, akin to the Mn heart of the oxygen evolving complicated of PSII, are nonetheless the point of interest of in-depth exam, either spectroscopic and structural. one other zone of outrage is the interplay among medicinal drugs and metals and steel ion antagonism. realizing the chemistry of steel ions in organic structures will deliver merits when it comes to knowing such difficulties as biomineralization and the construction of complicated fabrics via micro-organisms.
The 29 contributions to Bioinorganic Chemistry: An Inorganic viewpoint of Life provide a very good precis of the cutting-edge during this box, protecting components from the NMR of paramagnetic molecules to using lanthanide porphyrins in synthetic batteries.

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Extra resources for Bioinorganic Chemistry: An Inorganic Perspective of Life

Sample text

Serum transferrin is the iron transport agent of mammals. 1ts function and structure are increasingly weil understood, particularly because of the relatively recent protein crystal structure information. Transferrin not only acts as a transport agent but also functions as an iron buffer, maintaining free ferric ion concentrations in the body at a very low but constant value. This role of transferrin, and our understanding of the mechanisms of iron binding and release by the protein, are important in four areas of medical science.

Siderophore Mediated Iron Transport, VCH: New York, 1989, pp 1-121. (2) Otto, B. ; Verweij-van Vught, A. M. J. ; MacLaren, D. M. Grit. Rev. Microbiol. 1992,18,217-233. (3) Bullen, J. ; Ward, C. ; Rogers, H. J. Eur. 1. Microbiol. Infeet. Dis. 1991, 10,613617. ; Gill, P. R. Iron: A Modulator in Baeterial Virulenee and Symbiotie Nitrogen-Fixation; CRC Press: Boca Raton, 1992, pp 229-245. (5) Weinberg, E. D. ASM News 1993, 59, 559-562. ; al, e. Am. 1. Physiol. 1985,253, 1372-1380. (7) Hedlund, B. ; Hallaway, P.

1984,21,99-103. (36) Williarns, P. ; Warner, P. J. Infect. Immun 1980,29,411-416. ; Sansonetti, P. ; 1986 Infect. Immun. 1986, 54, 603-608. ; 0lson, M. O. ; Arceneaux, J. E. ; Clern, L. ; Byers, B. R. 1. Bacteriol. 1989, 171, 1811-1816. (39) Karpishin, T. ; Gebhard, M. ; Solornon, E. ; Raymond, K. N. 1. Am. ehem. Soc. 1991, 113,2977-2984. ; Raymond, K. N. 1. Am. ehem. Soc. 1974,96,6628-6630. (41) Isied, S. ; Raymond, K. N. 1. Am. ehem. Soc. 1976,98,1763-1767. ; Neilands, J. ; Raymond, K. N. Biochem.

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Bioinorganic Chemistry: An Inorganic Perspective of Life by Stephen J. Lippard (auth.), Dimitris P. Kessissoglou (eds.)


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